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🧬 Compensatory Mutations

Watch how deleterious mutations can be rescued by compensatory mutations through epistatic interactions. The fitness effect of mutations depends on what other mutations are present in the genome.

How much compensatory mutations restore fitness
Generation: 0
Avg Fitness: 1.00
Deleterious Muts: 0
Compensatory Muts: 0
Rescue Events: 0
Epistatic Pairs: 0
✨ Evolutionary Rescue! Compensatory mutation restored fitness.
Wild-type / Compensated
Deleterious mutation
Compensatory mutation
Epistatic interaction
Epistatic Compensation: Some mutations are only beneficial in the presence of specific deleterious mutations. This creates rugged fitness landscapes where evolutionary trajectories depend on mutation order.