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🧠 Neural Tube Formation

Neurulation: the neural plate folds to form the neural tube (future CNS). Cells undergo apical constriction, changing from columnar to wedge shape, causing tissue bending and tube closure.

Actin-myosin contraction
Generation: 0
Stage: Neural Plate
Fold Angle:
Closure: 0%
Tube Complete: No
Neurulation Mechanics:
1. Neural plate cells elongate (columnar)
2. Median hinge point forms (floor plate)
3. Neural folds elevate
4. Dorsolateral hinge points form
5. Neural folds meet and fuse (tube closure)
Defects → spina bifida, anencephaly